Europe Protein A Resins Market Share was valued at USD 131.9 million in 2019 and is expected to witness 8.4% CAGR from 2019 to 2026.
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Rising government expenditure on research and development will stimulate Europe protein A resins market growth. Protein A resin has been used widely for purification of monoclonal antibodies (mAb) in most of the drug discovery procedures. Drug discovery is gaining significant traction with growing incidence of infectious and chronic diseases. Additionally, expanding number of pharmaceutical and biotechnology industries will subsequently augment the regional protein A resins market size.
With growing adoption of chromatographic techniques for identification of additives in food industry will spur protein A resins market during the forecast timeline. Chromatography technique is frequently used in identification of biochemicals as well as for separation of biological substances. The demand for chromatography will surge due to numerous benefits offered as compared to traditional separation techniques. For biomanufacturing and capturing, recombinant mAb protein A resin is the most regularly used affinity resin for the process of chromatography. High reliability and better outcomes of chromatography due to protein A resins will thus drive the market size in the region.
Europe Market, By Application
Based on application, the market is segmented as immunoprecipitation (IP) and antibody purification. Immunoprecipitation segment held around USD 29 million revenue in 2019. IP is used for isolation of specific protein from complex mixtures such as tissue homogenate, blood sample and cell lysate. Immunoprecipitation (IP) is a small-scale enrichment of proteins. The process of IP is relatively easy and fast in comparison other chromatography techniques. Moreover, for the removal of immune complexes formed between an antigen and its specific antibody, protein A resins play a vital role. Thus, with wide application of immunoprecipitation in research and development sector, the segment will witness substantial growth.
Europe Market, By Product
Based on product, protein A resins market comprises natural protein A resins and recombinant protein A resins. Natural protein A segment is forecast to progress at over 8.2% CAGR during the analysis period. Owing to high capacity for antibody purification, natural protein A resins will witness robust growth in the future. However, natural protein A resins sensitivity to alkaline conditions can hamper the segmental size to a certain extent.
Europe Market, By Matrix Type
Based on matrix type, the market is segmented as agarose-based matrix, glass or silica gel-based matrix and organic polymer-based matrix. Glass or silica gel-based matrix segment held more than 9.5% revenue share in 2019. Owing to improved mechanical strength, improved durability and ability to absorb metallic dopants, the segment will witness significant growth in the forthcoming years.
Europe Market, By End-use
Based on end-use, the market is segmented as biopharmaceutical companies, clinical research laboratories, academic research institutes, and contract research organizations. Application of protein A resins in contract research organizations will foresee 8.2% CAGR in the forecast timeframe. Increasing R&D activities will be the chief factor responsible for segmental growth. Growing trend of outsourcing large-scale production to CROs will further augment the market size. Moreover, increasing drug delivery and research will increase the demand for contract research organizations in coming years.
Europe Market, By Country
Germany protein A resins market accounted for about USD 19.5 million revenue of the European protein A resins market in 2019. Rising drug discovery and development will provide considerable market growth. Presence of major market players in the country has significantly impacted the market growth. Also, rising demand for immunotherapy drugs for chronic diseases will further render significant market growth in the Germany.
Competitive Market Share
Some of the major industry players involved in Europe protein A resins market include GE Healthcare, Thermo Fisher Scientific, EMD Millipore, and Bio-Rad Laboratories among other market players. These companies are adopting strategies such as product differentiation and launch to garner significant market share in the industry. For instance, in November 2017, Repligen extended long term supply agreement with Purolite for Protein A Ligands, thereby assisting its product distribution.
With increasing demand of therapeutic antibodies, protein A resins market will witness significant growth. It is mainly used for chromatography technique for detection of vitamins and additives in the food. Protein A has been used for capturing monoclonal antibodies in most of the legal product submissions. The protein A chromatography performance such as operational flow rate, capacity, and its rate of monoclonal antibodies production was examined to gain insights for its consistent use. Since 1990 the adoption of protein A resins has rapidly increased with increasing clinical trials. Owing to its several advantages, protein A affinity chromatography has been used widely for monoclonal antibody products purification. Thus, with continuously increasing number of pharmaceutical companies and rapid adoption of chromatography in research industry, protein A resins market will grow rapidly in the foreseeable future.